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黑色素瘤的早期检测与筛查。国际现状。

The early detection of and screening for melanoma. International status.

作者信息

Koh H K, Geller A C, Miller D R, Lew R A

机构信息

Department of Dermatology, Boston University School of Medicine, MA 02118.

出版信息

Cancer. 1995 Jan 15;75(2 Suppl):674-83. doi: 10.1002/1097-0142(19950115)75:2+<674::aid-cncr2820751410>3.0.co;2-f.

Abstract

Cutaneous melanoma is an increasingly common public health problem in industrialized nations. In theory, education and early detection should decrease melanoma morbidity and mortality, because the lesion is external and visible, risk factors are known, and thin tumors are associated with a high 5-year survival rate. The efficacy of early detection and screening programs, however, remains untested by randomized trials. Some early data are available from melanoma prevention and control efforts that have begun in many nations over the past decade. Textbook definitions of cancer screening are particularly challenging when applied to skin cancer control. Although some propose that there are rigid differences among screening, education, and early detection of skin cancer, the visible nature of this cancer makes early detection through education and screening inextricably intertwined. This article discusses the intermediate measures of education and screening within the context of the American Academy of Dermatology programs. Over the next few decades, screening and education for melanoma and other skin cancer will receive increasing worldwide attention. Multiple strategies will be required to combat increasing incidence and mortality rates. Screening and educational programs have been implemented worldwide, but data on their effects are only just being collected. Future collaborative work in melanoma/skin cancer prevention, education, and early detection holds promise as a way to decrease mortality and save lives.

摘要

皮肤黑色素瘤在工业化国家正日益成为一个常见的公共卫生问题。理论上,教育和早期检测应能降低黑色素瘤的发病率和死亡率,因为该病变位于体表且可见,已知其风险因素,并且薄肿瘤与较高的5年生存率相关。然而,早期检测和筛查项目的效果尚未通过随机试验进行检验。过去十年中,许多国家已开展黑色素瘤预防和控制工作,从中可获取一些早期数据。当应用于皮肤癌控制时,癌症筛查的教科书定义尤其具有挑战性。尽管有人提出皮肤癌的筛查、教育和早期检测存在严格差异,但这种癌症的可见性使得通过教育和筛查进行早期检测紧密相连、不可分割。本文在美国皮肤病学会项目的背景下讨论教育和筛查的中间措施。在未来几十年里,黑色素瘤和其他皮肤癌的筛查和教育将在全球范围内受到越来越多的关注。需要多种策略来应对不断上升的发病率和死亡率。筛查和教育项目已在全球实施,但关于其效果的数据才刚刚开始收集。未来在黑色素瘤/皮肤癌预防、教育和早期检测方面的合作工作有望成为降低死亡率和挽救生命的途径。

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