Rossleigh M A, Thomas M Y, Moase A L
Department of Nuclear Medicine, Prince of Wales Hospital, Sydney Australia.
Clin Nucl Med. 1994 Oct;19(10):880-2. doi: 10.1097/00003072-199410000-00008.
In radionuclide diuresis renography, furosemide half-clearance times have been established using Tc-99m DTPA but have not been verified when Tc-99m MAG3 is used. One hundred and six consecutive diuretic renograms using Tc-99m MAG3 for the evaluation of unilateral renal abnormalities were assessed. The furosemide half-clearance times of the normal kidneys were all less than 9.8 minutes, with a mean of 3.4 minutes. In 18 patients, the half-clearance times of the normal kidney were artificially prolonged because urine had drained before the administration of the diuretic. The normal furosemide half-clearance time values obtained using Tc-99m MAG3 were found to be similar to those established for Tc-99m DTPA. Prolonged half-clearance times of Tc-99m MAG3 must be confirmed by visual evidence of obstruction.
在放射性核素利尿肾图检查中，速尿半清除时间已通过使用锝-99m二乙三胺五乙酸（Tc-99m DTPA）得以确立，但在使用锝-99m巯基乙酰三甘氨酸（Tc-99m MAG3）时尚未得到验证。对106例连续使用Tc-99m MAG3评估单侧肾脏异常情况的利尿肾图进行了分析。正常肾脏的速尿半清除时间均小于9.8分钟，平均为3.4分钟。在18例患者中，由于在给予利尿剂之前尿液已排出，正常肾脏的半清除时间被人为延长。发现使用Tc-99m MAG3获得的正常速尿半清除时间值与使用Tc-99m DTPA确立的值相似。Tc-99m MAG3半清除时间延长必须通过梗阻的视觉证据来证实。
