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[三尖瓣息肉状心内膜炎。一例心脏和肺部的形态学改变]

[Polypous endocarditis of the tricuspid valve. The morphological changes in the heart and lung in one case].

作者信息

Nachev S, Takov R

出版信息

Eksp Med Morfol. 1993;31(3-4):39-48.

PMID:7805619
Abstract

A case of polypous endocarditis which affects the tricuspid valve and whose genesis remains unclear (a septic state, an idiopathic disease?) is described. Clinically the disease has taken its course as a chronically recurring form of pulmonary thromboembolism. Morphologically it concerns to a massive fibroplastic verrucous endocarditis of the tricuspid valve and a more slightly expressed similar process in the wall of the right atrium and ventricle, combined with a significant fibrosis of the myocardium. The death has come from a massive thrombotic embolism in the two branches of the pulmonary artery on the background of a great number of small thromboembolic and hemorrhagenic infarctions with a different duration in the two lobes of the lung, which lead to an adaptable reconstruction of many lung vessels. The presence of a discrete affection of the aortic valve according to a rheumatic type and the combination of the disease, in the described case, with essential hypertension and thrombophlebitis undergone in the past, give a reason to discuss the possibility of taking into account these diseases in etiopathogenesis of the described myocardiopathy.

摘要

描述了一例影响三尖瓣且病因不明(败血症状态、特发性疾病?)的息肉状心内膜炎病例。临床上,该疾病呈慢性复发性肺血栓栓塞形式发展。形态学上,它表现为三尖瓣的大量纤维增生性疣状心内膜炎,右心房和心室壁也有较轻微的类似病变,并伴有心肌显著纤维化。患者死于肺动脉两个分支的大量血栓栓塞,在此之前两肺叶存在大量不同病程的小血栓栓塞性和出血性梗死,导致许多肺血管适应性重构。根据风湿类型,主动脉瓣存在离散性病变,且在所描述病例中该疾病与既往的原发性高血压和血栓性静脉炎并存,这使得有理由讨论在所述心肌病的病因发病机制中考虑这些疾病的可能性。

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