用于治疗精神分裂症的阿片类拮抗剂。

Opiate antagonists for the treatment of schizophrenia.

作者信息

Welch E B, Thompson D F

机构信息

Department of Pharmacy Practice, School of Pharmacy, Southwestern Oklahoma State University, Weatherford 73096.

出版信息

J Clin Pharm Ther. 1994 Oct;19(5):279-83. doi: 10.1111/j.1365-2710.1994.tb00814.x.

DOI:10.1111/j.1365-2710.1994.tb00814.x

PMID:7806598

Abstract

Numerous studies suggest that opiate antagonists may have antipsychotic properties. A review of the literature describing the use of naloxone to treat schizophrenic patients has shown mixed results. The three studies on naltrexone have found no benefit in controlling auditory hallucinations. We present a synopsis of these studies.

摘要

众多研究表明，阿片类拮抗剂可能具有抗精神病特性。一篇关于描述使用纳洛酮治疗精神分裂症患者的文献综述显示结果不一。三项关于纳曲酮的研究发现其在控制幻听方面并无益处。我们在此呈现这些研究的概要。