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儿童胃部肿瘤三例报告。

Report of three gastric tumors in children.

作者信息

Murphy S, Shaw K, Blanchard H

机构信息

Division of Pediatric General Surgery, Hôpital Sainte-Justine, Montreal, Quebec, Canada.

出版信息

J Pediatr Surg. 1994 Sep;29(9):1202-4. doi: 10.1016/0022-3468(94)90800-1.

Abstract

The literature concerning gastric tumors in children is mainly limited to case studies. The authors reviewed 1,403 histological reports of pediatric gastric pathology (covering 10 years) at their institution. There were three gastric tumors of benign histology and no malignant tumors. The first patient was a 9 1/2-year-old boy who presented with several months of symptomatic, pH-probe-confirmed gastroesophageal reflux. He underwent placement of a Toupet antireflux valve. During laparotomy, a submucosal mass was discovered incidentally, on the greater curvature of the stomach. The mass was excised. Pathological examination showed heterotopic pancreas. The second patient, a 15-month-old girl, presented with a short period of vomiting. Results of an upper gastrointestinal series showed gastric outlet obstruction. She underwent laparotomy and was found to have an intussusception of a gastric polyp into the proximal jejunum, and an associated malrotation. Ladd's procedure, gastroduoduodenostomy with reduction of the intussuscepted polyp, and excision of the polyp were performed. Histological examination of the tumor showed hamartoma with hyperplastic elements. The tumor was benign but was regarded as difficult to classify. The third patient, a 6-year-old boy, presented with microcytic anemia. Endoscopy showed multiple friable bleeding gastric masses. He underwent laparotomy, with partial gastrectomy and pyloroplasty. Histological examination showed the tumor to be plasma cell granuloma. The tumor recurred, and the patient required subsequent operative procedures. The authors confirm that gastric tumors in children are rare. Although the tumor histology may be benign, excision of the tumor may require major operative resection.

摘要

关于儿童胃肿瘤的文献主要局限于病例研究。作者回顾了他们机构10年间1403份儿童胃病理学组织学报告。其中有3例组织学为良性的胃肿瘤,无恶性肿瘤。首例患者是一名9岁半男孩,有几个月有症状的、经pH值探头证实的胃食管反流。他接受了Toupet抗反流瓣膜植入术。在剖腹手术中,偶然在胃大弯处发现一个黏膜下肿块。该肿块被切除。病理检查显示为异位胰腺。第二例患者是一名15个月大的女孩,有短期呕吐症状。上消化道造影结果显示胃出口梗阻。她接受了剖腹手术,发现有一个胃息肉套叠进入空肠近端,并伴有肠旋转不良。实施了Ladd手术、胃十二指肠吻合术以复位套叠的息肉并切除息肉。肿瘤的组织学检查显示为伴有增生成分的错构瘤。该肿瘤为良性,但被认为难以分类。第三例患者是一名6岁男孩,有小细胞贫血。内镜检查显示胃内有多个易碎的出血性肿块。他接受了剖腹手术,行部分胃切除术和幽门成形术。组织学检查显示肿瘤为浆细胞性肉芽肿。肿瘤复发,患者随后需要再次手术。作者证实儿童胃肿瘤很罕见。尽管肿瘤组织学可能为良性,但切除肿瘤可能需要进行较大范围的手术切除。

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