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智人脑部21 - 23千道尔顿蛋白(神经多肽h3)的氨基酸序列、与褐家鼠和牛相应蛋白的比较及其mRNA在不同组织中的表达

Amino acid sequence of the Homo sapiens brain 21-23-kDa protein (neuropolypeptide h3), comparison with its counterparts from Rattus norvegicus and Bos taurus species, and expression of its mRNA in different tissues.

作者信息

Seddiqi N, Bollengier F, Alliel P M, Périn J P, Bonnet F, Bucquoy S, Jollès P, Schoentgen F

机构信息

Laboratoire des protéines, CNRS URA 1188, Université Paris 5, France.

出版信息

J Mol Evol. 1994 Dec;39(6):655-60. doi: 10.1007/BF00160411.

Abstract

The amino acid sequence of neuropolypeptide h3 from Homo sapiens brain has been determined. It revealed that h3 is the exact counterpart of the 21-kDa protein from Bos taurus brain and the 23-kDa protein from Rattus norvegicus brain: The three proteins belong to the same 21-23-kDa protein family. Multiple tissue Northern blots showed that the mRNA encoding the 21-23-kDa protein is expressed in different amounts according to tissues and species; it is particularly abundant in Rattus norvegicus testis.

摘要

已确定来自智人脑部的神经多肽h3的氨基酸序列。结果显示,h3与来自牛脑部的21 kDa蛋白以及来自大鼠脑部的23 kDa蛋白完全对应:这三种蛋白属于同一个21 - 23 kDa蛋白家族。多组织Northern印迹分析表明,编码21 - 23 kDa蛋白的mRNA在不同组织和物种中的表达量有所不同;在大鼠睾丸中尤为丰富。

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