Maggio L, Gallini F, De Carolis M P, Frezza S, Greco F
Divisione di Neonatologia, Università Cattolica del Sacro Cuore, Roma.
Minerva Pediatr. 1994 Oct;46(10):421-7.
To evaluate the efficacy of a measure able to compare energy intake from parenteral and enteral nutrition we documented growth patterns in a group of VLBW infants treated with parenteral nutrition (PN). To analyze comparative energy intake from the two sources we expressed a percentage of both parenteral and enteral calories: the former (RCP%) related to an optimal value of 85 non protein calories and the latter (RCE%) to an optimal value of 150 total calories. Total energy intake was planned on the RCT% (RCP% + RCE%). We studied 75 VLBW infants with a mean BW of 1040 g and a mean GA of 29.5 weeks. The mean duration of PN was 25.8 +/- 10.4 days. The initial weight loss (10.2 +/- 5.3%), the time to regain BW (5.5 +/- 4 days) and the day of lowest weight (5.2 +/- 1.6 day of life) were in the normal range; the subsequent growth rate resulted 25.9 +/- 9.2 g/kg/die and did not change for different GA or BW. Growth pattern about head circumference and length were above the third percentile. The mean age of RCT% = 100% was 11.4 +/- 4.8 days of PN; this value was higher for the more premature infants. Severe metabolic abnormalities were not detected. Our observations show the efficacy of the RCT% as index of energy from both enteral and parenteral source during PN: the growth pattern seems to be quite satisfactory without any severe metabolic complication.
为评估一种能够比较肠外营养和肠内营养能量摄入的方法的疗效，我们记录了一组接受肠外营养（PN）治疗的极低出生体重儿的生长模式。为分析这两种营养来源的相对能量摄入，我们分别计算了肠外和肠内卡路里的百分比：前者（RCP%）相对于85非蛋白卡路里的最佳值，后者（RCE%）相对于150总卡路里的最佳值。总能量摄入根据RCT%（RCP% + RCE%）进行规划。我们研究了75例极低出生体重儿，平均出生体重为1040克，平均胎龄为29.5周。PN的平均持续时间为25.8 +/- 10.4天。初始体重减轻（10.2 +/- 5.3%）、恢复出生体重的时间（5.5 +/- 4天）和最低体重日（出生后5.2 +/- 1.6天）均在正常范围内；随后的生长速率为25.9 +/- 9.2克/千克/天，且不因不同的胎龄或出生体重而改变。头围和身长的生长模式高于第三百分位。RCT% = 100%时的平均年龄为PN开始后11.4 +/- 4.8天；胎龄越小的婴儿该值越高。未检测到严重的代谢异常。我们的观察结果表明，RCT%作为PN期间肠内和肠外营养能量指标是有效的：生长模式似乎相当令人满意，且无任何严重的代谢并发症。
