Gallini F, Zecca E, Maggio L, Tortorolo L, Papacci P, Marrocco G
Divisione Neonatologica, Università Cattolica del Sacro Cuore, Roma.
Minerva Pediatr. 1992 Jun;44(6):285-91.
This study was designed to verify the effectiveness of parenteral nutrition (NP) and continuous nasogastric feeding (AOG) in providing a good caloric intake and a good growth in the very low birth weight infants during the first 60 days of life. The study included 108 preterm babies with birth weight less than or equal to 1500 g: 26 received parenteral nutrition, 82 nasogastric feeding. Infants in NP showed a smaller postnatal weight loss and regained birth weight earlier than the AOG group. Caloric intake greater than 120 kcal/kg/die was achieved in 10.2 days of life in the NP group and in 14.1 days in the AOG group. Full enteral feeding was achieved later in the NP than in the AOG group (25.7 days vs 20.7 days). Weight gain at 60 days of life was better in the NP group (23.2 g/die vs 18.2 g/die), while there was no difference in the head circumference gain. The study shows the efficacy of NP in providing a good caloric intake in the very low birth weight infants in the first weeks of life.
本研究旨在验证肠外营养（PN）和持续鼻胃管喂养（NG）在极低出生体重儿出生后前60天提供充足热量摄入及良好生长发育方面的有效性。该研究纳入了108例出生体重小于或等于1500克的早产儿：26例接受肠外营养，82例接受鼻胃管喂养。接受肠外营养的婴儿出生后体重下降幅度较小，且比鼻胃管喂养组更早恢复出生体重。肠外营养组在出生后10.2天达到大于120千卡/千克/天的热量摄入，鼻胃管喂养组则在14.1天达到。肠外营养组实现完全肠内喂养的时间比鼻胃管喂养组晚（25.7天对20.7天）。出生后60天时，肠外营养组的体重增长情况更好（23.2克/天对18.2克/天），而头围增长无差异。该研究表明，肠外营养在极低出生体重儿出生后的最初几周提供充足热量摄入方面具有有效性。
