次氯酸盐水溶液简单酸化时单重态分子氧的产生：应用于氯化饮用水对健康有害影响的研究。
Singlet molecular oxygen evolution upon simple acidification of aqueous hypochlorite: application to studies on the deleterious health effects of chlorinated drinking water.
作者信息
Khan A U, Kasha M
机构信息
Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138.
出版信息
Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12362-4. doi: 10.1073/pnas.91.26.12362.
Abstract
A study of the pH profile of the decomposition of aqueous hypochlorite has revealed the evolution (onset at pH 8) of single (1 delta g) molecular oxygen (singlet spin state dioxygen) detected spectroscopically (1268 nm), prior to the appearance of chlorine (onset at pH 5.5). The possible mechanism of the singlet state dioxygen evolution is presented, and the origin of its chloride ion dependence is discussed, especially in reference to chloride ion dependence of singlet molecular oxygen evolution in biological systems. Recent epidemiological analyses of the correlation of human cancer with chlorinated water supplies focus attention on the singlet oxygen mechanisms of DNA lesion formation.
摘要
一项关于次氯酸盐水溶液分解的pH值曲线研究表明，在氯出现（起始pH值为5.5）之前，通过光谱检测（1268纳米）发现了单重态（1Δg）分子氧（单重自旋态双氧）的生成（起始pH值为8）。文中提出了单重态双氧生成的可能机制，并讨论了其对氯离子依赖性的起源，特别是参照了生物系统中生成单重态分子氧对氯离子的依赖性。最近关于人类癌症与氯化供水相关性的流行病学分析，将注意力集中在DNA损伤形成的单线态氧机制上。
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本文引用的文献
1
Direct spectroscopic observation of singlet oxygen emission at 1268 nm excited by sensitizing dyes of biological interest in liquid solution.在液体溶液中，通过具有生物学意义的敏化染料激发，对1268纳米处单线态氧发射进行直接光谱观测。
Proc Natl Acad Sci U S A. 1979 Dec;76(12):6047-9. doi: 10.1073/pnas.76.12.6047.
2
Myeloperoxidase singlet molecular oxygen generation detected by direct infrared electronic emission.通过直接红外电子发射检测髓过氧化物酶单线态分子氧的产生。
Biochem Biophys Res Commun. 1984 Jul 31;122(2):668-75. doi: 10.1016/s0006-291x(84)80085-6.
3
The role of chloride ion in photosynthesis. 3. The effect of artificial electron donors upon electron transport.氯离子在光合作用中的作用。3. 人工电子供体对电子传递的影响。
Biochim Biophys Acta. 1969 Jun 24;180(2):388-98. doi: 10.1016/0005-2728(69)90123-6.
4
Singlet molecular oxygen causes loss of biological activity in plasmid and bacteriophage DNA and induces single-strand breaks.
Biochim Biophys Acta. 1989 Mar 1;1007(2):151-7. doi: 10.1016/0167-4781(89)90033-x.
5
Singlet oxygen induces frank strand breaks as well as alkali- and piperidine-labile sites in supercoiled plasmid DNA.
Photochem Photobiol. 1989 May;49(5):607-13. doi: 10.1111/j.1751-1097.1989.tb08431.x.
6
Nucleotide chloramines and neutrophil-mediated cytotoxicity.核苷酸氯胺与中性粒细胞介导的细胞毒性。
FASEB J. 1991 Mar 1;5(3):295-300. doi: 10.1096/fasebj.5.3.1848195.
7
Biological consequences associated with DNA oxidation mediated by singlet oxygen.
J Photochem Photobiol B. 1991 Dec;11(3-4):241-60. doi: 10.1016/1011-1344(91)80030-l.
8
Chlorination, chlorination by-products, and cancer: a meta-analysis.氯化、氯化副产物与癌症：一项荟萃分析。
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9
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