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[高产科风险人群中的生殖微生物群落]

[Genital microbial flora in a population of high obstetrical risk].

作者信息

Villagra C E, Martínez M A, Ovalle A

机构信息

Departamento de Microbiología, Facultad de Medicina, Unviersidad de Chile.

出版信息

Rev Chil Obstet Ginecol. 1994;59(1):32-8.

PMID:7809430
Abstract

There is increasing evidence showing the association between maternal genital infection, prematurity and neonatal or maternal morbidity. To know the genital flora of women attending a high risk pregnancy service, 73 consecutive pregnant women attending the high risk pregnancy service at the Hospital San Borja-Arriarán from may to august 1992 were included in this study, 75.3% of the vaginal discharges corresponded to fluids of normal appearance and 24.7% were altered. The microorganisms most frequently isolates were lactobacilli, U. urealitycum and coagulase negative strains of Staphylococcus. The Gram stain revealed the existence of bacterial vaginosis in 20.9% of the vaginal smears. There was a significant higher incidence of lactobacilli in patients with balanced healthy vaginal flora, whereas Gardnerella vaginalis and Mycoplasma hominis were isolated significantly more frequently from women with bacterial vaginosis. With the exception of genital mycoplasma, it was found a low incidence of sex transmitted bacteria in this study.

摘要

越来越多的证据表明,孕产妇生殖器感染、早产与新生儿或孕产妇发病之间存在关联。为了解高危妊娠服务机构中女性的生殖菌群情况,本研究纳入了1992年5月至8月在圣博尔哈 - 阿里亚兰医院高危妊娠服务机构就诊的73名连续孕妇,75.3%的阴道分泌物外观正常,24.7%出现异常。最常分离出的微生物是乳酸杆菌、解脲脲原体和凝固酶阴性葡萄球菌菌株。革兰氏染色显示20.9%的阴道涂片存在细菌性阴道病。阴道菌群平衡健康的患者中乳酸杆菌的发生率显著更高,而加德纳菌和人型支原体在细菌性阴道病女性中分离出的频率显著更高。除生殖支原体外,本研究中发现性传播细菌的发生率较低。

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