León-S F E, Zaninovic V, Osame M, Arimura K, Arimura Y
Third Department of Internal Medicine, Kagoshima University School of Medicine, Japan.
Rev Med Chil. 1994 Mar;122(3):265-73.
Tropical spastic paraparesis is the same clinical entity all over the world. It has been suggested that some clinical presentation differences are due to not well defined environmental factors that act along with the virus, modifying the start and progression of the disease. We analyzed 25 publications on the disease coming from different parts of the world, aiming to unravel regional differences. In these reports, we found different degrees of subclinical abnormalities in visual and somatosensory evoked potentials, nerve conduction studies, superior and inferior limb F wave and electromyography. It is concluded that genetic, environmental and even cultural factors may influence the clinical presentation of tropical spastic paraparesis and explain the detected differences in the reports analyzed in this study.
热带痉挛性截瘫在全球范围内是同一种临床病症。有人认为，一些临床表现差异是由于与病毒共同作用的环境因素定义不明确，这些因素改变了疾病的起始和进展。我们分析了来自世界不同地区的25篇关于该疾病的出版物，旨在揭示地区差异。在这些报告中，我们发现视觉和体感诱发电位、神经传导研究、上肢和下肢F波以及肌电图存在不同程度的亚临床异常。得出的结论是，遗传、环境甚至文化因素可能影响热带痉挛性截瘫的临床表现，并解释本研究分析的报告中检测到的差异。
