[The role of the limbic cortex in regulating the neuronal impulse activity of the respiratory center in the medulla oblongata under conditions of oxygen deficiency].

Complex action of hypoxia and electrostimulation of the limbic cortex on unit activity of bulbar respiratory neurons was studied. Under normal barometric pressure the influence of the limbic electrostimulation on activity of bulbar respiratory neurons was ambiguous, i.e., both activation and inhibition were observed, but inhibitory influences prevailed. In initial phase (4000-5000 m) at the background of hypoxic activation the influence of electrostimulation of the limbic cortex on activity of respiratory neurons was predominantly inhibitory, as under conditions of normoxia. In the phase of severe hypoxia (7500-8000 m) at the background of expressed hypoxic suppression of activity of respiratory neurons stimulation of the limbic cortex did not induce reactions characteristic of these neurons. Reaction of the respiratory neurons on the electrical stimulation of the limbic cortex in different phases of hypoxic action depended on relatively high sensitivity to hypoxia of the limbic cortex and the functional state of the bulbar respiratory center.