Akopian N S, Baklavadzhian O G, Karapetian M A
Fiziol Zh SSSR Im I M Sechenova. 1983 May;69(5):623-9.
The changes of respiratory neurons (RS) activity had a phasic character in acute hypoxia. At the initial stage of the hypoxia (the altitude 4000-5000 m), the firing rate of inspiratory (IN) and expiratory (EN) neurons was increasing whereas at the maximum altitude (8000-9000 m) it was decreasing. After the descent, the background RN activity restored. The comparative analysis of RN resistance to hypoxia showed higher resistance of IN than of EN which determined the entire reaction of the respiratory system, viz. the more stable phase of inspiration. A great number of IN were revealed at the altitude of 8000-9000 m which had been in the state of inhibition for a long time under conditions of normoxia but became activated with the acute oxygen deficiency.
在急性缺氧时，呼吸神经元（RS）活动的变化具有阶段性特征。在缺氧初期（海拔4000 - 5000米），吸气（IN）和呼气（EN）神经元的放电频率增加，而在最高海拔（8000 - 9000米）时则降低。下降后，呼吸神经元的背景活动恢复。对呼吸神经元对缺氧抗性的比较分析表明，吸气神经元比呼气神经元具有更高的抗性，这决定了呼吸系统的整体反应，即吸气阶段更稳定。在海拔8000 - 9000米处发现大量吸气神经元，它们在常氧条件下长期处于抑制状态，但在急性缺氧时被激活。
