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[嗅球对延髓呼吸中枢网状神经元在低氧状态下的影响]

[The influence of bulbus olfactorius at the reticular neurons of bulbar respiratory center in hypoxia].

作者信息

Karapetian M A, Adamian N Iu, Arutiunian R S

出版信息

Ross Fiziol Zh Im I M Sechenova. 2012 Jun;98(6):767-76.

PMID:23013014
Abstract

Under conditions of oxygen deficiency the influence of electrical stimulation of bulbus olfactorius on the impulse activity of reticular neurons of bulbar respiratory center was studied. Under conditions ofnormoxia both activation and inhibition of impulse activity of bulbar respiratory neurons are observed with a predominance of stimulating action. The changes in the dynamic of hypoxia had phase character. At the initial stage of oxygen deficiency (4000-5000 m altitude), during hypoxic activation, the stimulating action of bulbus olfactorius is less expressed than under the conditions ofnormoxia. At the second stage ofhypoxia (7500-8000 m altitude) the stimulating influence of this nucleus was significant.

摘要

在缺氧条件下,研究了电刺激嗅球对延髓呼吸中枢网状神经元冲动活动的影响。在常氧条件下,观察到延髓呼吸神经元冲动活动的激活和抑制,刺激作用占主导。缺氧动态变化具有阶段性特征。在缺氧初期(海拔4000 - 5000米),缺氧激活时,嗅球的刺激作用比常氧条件下表现得弱。在缺氧第二阶段(海拔7500 - 8000米),该核团的刺激影响显著。

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