Schnaudigel O E, Gümbel H, Richter R, Subklew R, Garweg T
Zentrum der Augenheilkunde, Universität Frankfurt/M.
Ophthalmologe. 1994 Oct;91(5):668-70.
In a prospective study of 101 patients with HIV infection and a medium CD4 lymphocyte cell count of 350 x 10(6)/l and a retrospective study of the records of 79 AIDS patients, we compared the first ocular symptoms in HIV-infected patients to the CD4 count. In Walter-Reed stages 2-4 (n = 101) we found sicca syndrome in 9.2%, in 52% lens opacities in the cortex and only in less than 1% HIV-related angiopathy of the retina. In Walter Reed stages 5-6 (n = 79), 26% of the AIDS patients developed CMV retinitis, 33% HIV angiopathy of the retina and only 1% retinal toxoplasmosis. The average CD4 lymphocyte cell count was never better than 100 x 10(6). Lens opacities in HIV-infected patients could be an early ophthalmological symptom of HIV infection.
在一项针对101例HIV感染患者（CD4淋巴细胞计数中位数为350×10⁶/l）的前瞻性研究以及一项对79例艾滋病患者病历的回顾性研究中，我们将HIV感染患者的首发眼部症状与CD4计数进行了比较。在沃尔特·里德2 - 4期（n = 101），我们发现9.2%的患者有干燥综合征，52%的患者晶状体皮质混浊，而视网膜HIV相关性血管病变的患者不到1%。在沃尔特·里德5 - 6期（n = 79），26%的艾滋病患者发生了巨细胞病毒性视网膜炎，33%的患者有视网膜HIV血管病变，仅有1%的患者有视网膜弓形虫病。CD4淋巴细胞计数平均值从未超过100×10⁶。HIV感染患者的晶状体混浊可能是HIV感染的早期眼科症状。
