Probst P, Hermann E, Fleischer B
Bernhard-Nocht Institute for Tropical Medicine, Germany.
Trends Microbiol. 1994 Sep;2(9):329-32. doi: 10.1016/0966-842x(94)90450-2.
Reactive arthritis is a usually self-limited sterile inflammation of joints that follows certain bacterial gastrointestinal or urogenital infections. The immunopathogenesis involves CD4+ T cells, which mediate an antigen-specific TH1 response to bacterial constituents within the joint. Properties of the arthritogenic bacteria and the physicochemical characteristics of the bacterial antigens may contribute to the development of reactive arthritis.
反应性关节炎是一种通常为自限性的关节无菌性炎症，继发于某些细菌引起的胃肠道或泌尿生殖道感染。免疫发病机制涉及CD4 + T细胞，其介导针对关节内细菌成分的抗原特异性TH1反应。致关节炎细菌的特性和细菌抗原的物理化学特征可能有助于反应性关节炎的发生。
