Chen I C, Yeh S J, Wen M S, Lin F C, Wu D
Department of Medicine, Chang Gung Memorial Hospital, Chang Gung Medical College, Taipei, Taiwan.
Chest. 1995 Jan;107(1):41-5. doi: 10.1378/chest.107.1.41.
An electrophysiologic study followed by transcatheter radiofrequency ablation therapy was performed in two adult patients with a permanent form of junctional tachycardia. Both patients had no structural heart disease and exhibited a normal resting ECG. The P wave during tachycardia was negative in leads 1, 3, and aVF, biphasic over V6, and positive in V1 and aVL in both patients, while the P-R/R-P interval ratio during tachycardia was 0.82 and 0.36, respectively, in both patients. Both patients displayed an eccentric atrial activation sequence with the earliest atrial activation occurring at the distal coronary sinus and a decremental retrograde conduction property during incremental ventricular pacing, suggesting the presence of a concealed slowly conducting left free wall accessory pathway. The tachycardia used the normal atrioventricular pathway for anterograde conduction and the concealed show left accessory pathway for retrograde conduction. It was terminated following adenosine administration in both patients; termination of tachycardia was due to a block in the retrograde accessory pathway in one patient and due to a block in the atrioventricular node in the other patient. Radiofrequency ablation was performed by the retrograde transaortic approach. The radiofrequency f4p4ent was delivered to the site of the earliest atrial activation during tachycardia at the ventricular aspect of the mitral annulus. The successful ablation site had a ventriculoatrial (VA) interval of 120 and 130 ms, respectively, and was located at the posterolateral and lateral aspects of the mitral annulus. Following ablation, there was no VA conduction; however, conduction through the normal atrioventricular pathway was noted during isoproterenol infusion in both patients. There was no induction of tachycardia. This study demonstrates that the permanent form of junctional tachycardia in adults can incorporate a concealed left free wall accessory pathway with a decremental property. Radiofrequency ablation therapy is effective and safe in this form of arrhythmia.
对两名患有永久性交界性心动过速的成年患者进行了电生理研究,随后进行了经导管射频消融治疗。两名患者均无结构性心脏病,静息心电图正常。两名患者心动过速时,I、III和aVF导联的P波为负向,V6导联呈双向,V1和aVL导联为正向,而心动过速时的P-R/R-P间期比值分别为0.82和0.36。两名患者均表现为偏心性心房激动顺序,最早的心房激动发生在冠状窦远端,在心室递增起搏时具有递减的逆向传导特性,提示存在隐匿性缓慢传导的左游离壁旁路。心动过速时前向传导通过正常房室通路,逆向传导通过隐匿性左旁路。两名患者在给予腺苷后心动过速均终止;一名患者心动过速终止是由于逆向旁路阻滞,另一名患者是由于房室结阻滞。通过逆行经主动脉途径进行射频消融。将射频能量传递至心动过速时二尖瓣环心室侧最早心房激动的部位。成功的消融部位的室房(VA)间期分别为120和130毫秒,位于二尖瓣环的后外侧和外侧。消融后,无VA传导;然而,两名患者在静脉滴注异丙肾上腺素期间均记录到通过正常房室通路的传导。未诱发心动过速。本研究表明,成人永久性交界性心动过速可合并具有递减特性的隐匿性左游离壁旁路。射频消融治疗这种心律失常有效且安全。