Coates R J, Greenberg R S, Liu M T, Correa P, Harlan L C, Reynolds P, Fenoglio-Preiser C M, Haynes M A, Hankey B F, Hunter C P
Epidemiology Division, Emory School of Public Health, Atlanta, Georgia 30322.
Dis Colon Rectum. 1995 Jan;38(1):42-50. doi: 10.1007/BF02053856.
Black patients with colon cancer are more likely to have poorer survival from colon cancer than are white patients. To determine whether anatomic site differences might contribute to survival differences, we compared anatomic site distributions of black and white patients.
As part of the Black/White Cancer Survival Study, we collected medical record data for 1,045 patients from Atlanta, New Orleans, and San Francisco/Oakland, newly diagnosed in 1985 or 1986 and interviewed 745 of them.
In polychotomous logistic regression analysis, site was related to stage, grade, and histologic type and among women with age, parity, and possibly smoking. However, it was not related to race, except perhaps among men age 65 and older, among whom blacks were somewhat likely to have more transverse and distal, not proximal, cancer. These relations were consistent across subgroups and were independent of other factors examined.
Results suggest that site differences are unlikely to contribute to poorer survival commonly observed among black colon cancer patients in the United States.
与白人结肠癌患者相比，黑人结肠癌患者的生存预后往往更差。为了确定解剖部位差异是否可能导致生存差异，我们比较了黑人和白人患者的解剖部位分布情况。
作为黑/白癌症生存研究的一部分，我们收集了1985年或1986年新诊断出的来自亚特兰大、新奥尔良和旧金山/奥克兰的1045例患者的病历数据，并对其中745例进行了访谈。
在多分类逻辑回归分析中，解剖部位与分期、分级、组织学类型相关，在女性中还与年龄、产次以及可能的吸烟情况相关。然而，它与种族无关，可能65岁及以上男性除外，在这些男性中，黑人患横结肠癌和远端结肠癌而非近端结肠癌的可能性略高。这些关系在各亚组中是一致的，并且独立于所研究的其他因素。
结果表明，解剖部位差异不太可能导致美国黑人结肠癌患者中常见的较差生存情况。
