Moreno C, Ardanaz E, Olivera J E, Castilla J, de Pedro-Cuesta J
Section of Epidemiological Surveillance, Institute of Public Health, Pamplona, Spain.
Eur J Epidemiol. 1994 Apr;10(2):129-34. doi: 10.1007/BF01730361.
An apparent temporal-spatial cluster of Sudden Infant Death Syndrome (SIDS) was noted in the Autonomous Community of Navarre, Spain, when four unrelated children aged between 1 and 6 months died unexpectedly within a 7-day interval in January, 1990. The population under one year of age in Navarre was approximately 4,800. The scan test of temporal clustering showed that the sudden infant deaths occurred closer to one another in time significantly more often than would be expected by chance. All four infants lived in a neighbourhood of the capital of Navarre, which accounts for approximately half the region's population. The clustered cases coincided with an outbreak of influenza type A detected by the epidemiological surveillance system and seen by the increase in 1990 over the same period in the previous year in the number of paediatric emergency-ward admissions during the 'epidemic' days. The results confirm the presence of a temporal-spatial cluster of SIDS and favour an environmental etiology where exposure to influenza A viruses is implicated.
1990年1月，在西班牙纳瓦拉自治区发现了明显的婴儿猝死综合征（SIDS）时空聚集现象，当时有4名年龄在1至6个月之间的互不相关儿童在7天内意外死亡。纳瓦拉一岁以下的人口约为4800人。时间聚集的扫描测试表明，婴儿猝死在时间上比偶然预期的更为频繁地彼此靠近发生。所有4名婴儿都居住在纳瓦拉首府的一个街区，该街区约占该地区人口的一半。聚集性病例与流行病学监测系统检测到的甲型流感爆发同时出现，1990年“流行”期间儿科急诊病房入院人数较上一年同期有所增加。结果证实了SIDS存在时空聚集现象，并支持暴露于甲型流感病毒的环境病因学。
