Zink P, Drescher J, Verhagen W, Flik J, Milbradt H
Arch Virol. 1987;93(3-4):223-32. doi: 10.1007/BF01310976.
40 forensic SIDS cases were found to have a significantly higher rate of serologic evidence of recent influenza A (H 3 N 2) infection than did matched controls. In contrast, the SIDS cases had serologically no significantly increased infection rate with influenza H 1 N 1 and B virus, parainfluenza virus, RS virus, adenovirus, and cytomegalovirus. SIDS cases with recent influenza infection had a significantly higher rate of histological findings as described for primary viral pneumonia than did SIDS cases without influenza infection. SIDS cases with recent influenza infection occurred much more frequently during epidemic than during interepidemic influenza A (H 3 N 2) periods. Our results confirm previous reports that SIDS cases have an increased rate of respiratory virus infections. However, they cannot prove a causal relationship between influenza infection and death. Since our SIDS cases comprised 75 per cent of cases aged more than three months, our results pertain essentially to cases of this age group.
40例法医判定的婴儿猝死综合征（SIDS）病例被发现近期感染甲型（H3N2）流感的血清学证据发生率显著高于匹配的对照组。相比之下，SIDS病例感染H1N1流感病毒、B型流感病毒、副流感病毒、呼吸道合胞病毒（RS病毒）、腺病毒和巨细胞病毒的血清学感染率并无显著增加。近期感染流感的SIDS病例出现原发性病毒性肺炎组织学表现的发生率显著高于未感染流感的SIDS病例。近期感染流感的SIDS病例在甲型（H3N2）流感流行期间比在非流行期间更为频繁地出现。我们的结果证实了先前的报道，即SIDS病例呼吸道病毒感染率增加。然而，它们无法证明流感感染与死亡之间存在因果关系。由于我们的SIDS病例占三个月以上婴儿病例的75%，我们的结果主要适用于该年龄组的病例。
