Pell J P, Fowkes F G, Ruckley C V, Clarke J, Kendrick S, Boyd J H
Wolfson Unit for Prevention of Peripheral Vascular Diseases, University of Edinburgh, U.K.
Eur J Vasc Surg. 1994 Sep;8(5):602-6. doi: 10.1016/s0950-821x(05)80598-5.
To determine time trends and geographical variations in the incidence of major amputation for peripheral arterial disease and whether lower rates of amputation were related to higher rates of arterial reconstruction.
Analysis of Scottish hospital discharge data.
Scotland 1981-1990.
Patients undergoing major amputation or arterial reconstruction for peripheral arterial disease.
Time trends in age-sex standardised rates of major amputation and arterial reconstruction, and correlation between the rates of these operations by health board.
In Scotland, between 1981 and 1990, the incidence of major amputation fell by 22% (p < 0.001). Inconsistencies were observed within different age-sex groups. In the population under 65 years of age the incidence of amputation fell by 45% (p < 0.001), whereas in those over 65 years the incidence increased by 54% (p < 0.001). Amputation rates fell in men but a paradoxical increase was observed in women. Between 1981 and 1990, rates of arterial reconstruction doubled (p < 0.001), with an increase in all age-sex groups. Rates of amputation and reconstruction varied between health boards of residence, with a positive correlation (r = 0.5) between rates of operations within health board. Therefore areas with higher reconstruction rates tended to have higher amputation rates.
In Scotland, the incidence of amputation has fallen during a period when reconstruction rates have risen greatly. However inconsistencies in time trends by age-sex groups, and the lack of an inverse correlation by health board of residence, suggest that fewer amputations are unlikely to be due solely to an increase in reconstructive surgery.
确定外周动脉疾病大截肢发生率的时间趋势和地理差异,以及较低的截肢率是否与较高的动脉重建率相关。
对苏格兰医院出院数据进行分析。
1981 - 1990年的苏格兰。
因外周动脉疾病接受大截肢或动脉重建的患者。
大截肢和动脉重建的年龄 - 性别标准化率的时间趋势,以及按卫生委员会划分的这些手术率之间的相关性。
在苏格兰,1981年至1990年间,大截肢的发生率下降了22%(p < 0.001)。不同年龄 - 性别组之间存在不一致情况。在65岁以下人群中,截肢发生率下降了45%(p < 0.001),而在65岁以上人群中,发生率增加了54%(p < 0.001)。男性的截肢率下降,但女性出现了反常的增加。1981年至1990年间,动脉重建率翻了一番(p < 0.001),所有年龄 - 性别组均有增加。截肢率和重建率在居住的卫生委员会之间有所不同,同一卫生委员会内手术率之间存在正相关(r = 0.5)。因此,重建率较高的地区往往截肢率也较高。
在苏格兰,截肢发生率在重建率大幅上升的时期有所下降。然而,年龄 - 性别组时间趋势的不一致,以及按居住卫生委员会划分缺乏负相关,表明截肢减少不太可能仅仅归因于重建手术的增加。