成人唐氏综合征与甲状腺功能
Down syndrome and thyroid function in adults.
作者信息
Baxter R G, Larkins R G, Martin F I, Heyma P, Myles K, Ryan L
出版信息
Lancet. 1975 Oct 25;2(7939):794-6. doi: 10.1016/s0140-6736(75)80007-9.
PMID:78156
Abstract
Thyroid function has been studied in 11 middle-aged and elderly subjects with proven Down syndrome. Unequivaocal biochemical evidence of hypothyroidism was found in 6, and of thyrotoxicosis in 1. It is concluded that, in contrast to the situation in children with Down syndrome, thyroid dysfunction is exceedingly common in adults with the syndrome.
摘要
对11名经证实患有唐氏综合征的中老年受试者的甲状腺功能进行了研究。在6名受试者中发现了明确的甲状腺功能减退的生化证据，1名受试者有甲状腺毒症的证据。得出的结论是，与唐氏综合征儿童的情况相反，甲状腺功能障碍在患有该综合征的成年人中极为常见。
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