Kovanecz I, Csajbók E, Petri I B
Blood Transfusion Centre, Albert Szentgyörgyi Medical University, Szeged, Hungary.
Nephrol Dial Transplant. 1994;9(10):1474-6.
We studied in-vitro steroid sensitivity using the test of ADCC in 207 haemodialysed chronic uremic patients, 85 renal transplant patients, and 75 healthy blood donors as normal controls. The association of HLA phenotypes with the in-vitro steroid sensitivity was assessed. The proportion of steroid-sensitive subjects was significantly higher in the normal control group than in the patients. A significant association was observed between HLA B8 carriers and steroid resistance and between HLA DR6 carriers and steroid sensitivity.
我们使用抗体依赖的细胞介导的细胞毒性（ADCC）试验，对207例接受血液透析的慢性尿毒症患者、85例肾移植患者以及75名健康献血者作为正常对照进行了体外类固醇敏感性研究。评估了HLA表型与体外类固醇敏感性之间的关联。正常对照组中类固醇敏感受试者的比例显著高于患者组。观察到HLA B8携带者与类固醇抵抗之间以及HLA DR6携带者与类固醇敏感性之间存在显著关联。
