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[中度严重慢性阻塞性肺疾病通气阈值水平个体化康复的价值]

[Value of individualized rehabilitation at the ventilatory threshold level in moderately severe chronic obstructive pulmonary disease].

作者信息

Vallet G, Varray A, Fontaine J L, Préfaut C

机构信息

Clinique du Souffle, La Solane, Osseja.

出版信息

Rev Mal Respir. 1994;11(5):493-501.

PMID:7816993
Abstract

In order to study the efficiency of individual training programs at the ventilatory threshold level, twenty COPD patients were randomized into two groups and studied over a two-month period. At the start, during, and at the end of the study all subjects performed incremental exercise tests. The trained group (59.60 SEM +/- 2.75 years) walked four times a week at the heart rate corresponding to the metabolic level of ventilatory threshold. The other group served as controls (58.2 +/- 1.80 years). A marked increase in the symptom-limited oxygen consumption (+/- 25%) (p < 0.01), the maximal ventilation (+20%) (p < 0.01), and the ventilatory threshold (+19%) (p < 0.05) was found in the trained group. No modification was recorded in the control group. The ventilatory pattern at submaximal intensities expressed in percentage of the initial oxygen consumption showed significant differences between groups, the trained-group ventilation decreased at 50% and 75% VO2 sl (p < 0.05). The breathing frequency also decreased at 50% and 75% VO2 sl (p > 0.05). Moreover, we observed an increase in the oxygen pulse at 50% VO2 sl (p < 0.05). In conclusion, this study demonstrates that individualized training at the ventilatory threshold level increases exercise tolerance and produces better ventilatory comfort in COPD patients.

摘要

为研究通气阈值水平下个体训练计划的效果,将20例慢性阻塞性肺疾病(COPD)患者随机分为两组,并进行了为期两个月的研究。在研究开始、进行期间和结束时,所有受试者均进行了递增运动试验。训练组(年龄59.60±2.75岁)每周四次以对应通气阈值代谢水平的心率进行步行训练。另一组作为对照组(年龄58.2±1.80岁)。训练组患者症状限制耗氧量显著增加(±25%)(p<0.01)、最大通气量增加(+20%)(p<0.01)、通气阈值增加(+19%)(p<0.05)。对照组未见变化。以初始耗氧量百分比表示的次最大强度通气模式在两组间存在显著差异,训练组在50%和75%VO2sl时通气量下降(p<0.05)。呼吸频率在50%和75%VO₂sl时也下降(p>0.05)。此外,我们观察到在50%VO₂sl时氧脉搏增加(p<0.05)。总之,本研究表明,通气阈值水平的个体化训练可提高COPD患者的运动耐力并产生更好的通气舒适度。

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[Value of individualized rehabilitation at the ventilatory threshold level in moderately severe chronic obstructive pulmonary disease].[中度严重慢性阻塞性肺疾病通气阈值水平个体化康复的价值]
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引用本文的文献

1
Pulmonary rehabilitation for chronic obstructive pulmonary disease.慢性阻塞性肺疾病的肺康复治疗
Cochrane Database Syst Rev. 2015 Feb 23;2015(2):CD003793. doi: 10.1002/14651858.CD003793.pub3.
2
Does pulmonary rehabilitation work in clinical practice? A review on selection and dropout in randomized controlled trials on pulmonary rehabilitation.肺康复在临床实践中有效吗?一项关于肺康复随机对照试验中选择和脱落的综述。
Clin Epidemiol. 2010 Aug 9;2:73-83. doi: 10.2147/clep.s9483.