在种族多样化人群中进行的结直肠癌粪便潜血检测。
Fecal occult blood testing for colorectal cancer in an ethnically diverse population.
作者信息
Glober G A, Hundahl S, Stucke J, Choy M
机构信息
Department of Gastrointestinal Medical Oncology and Digestive Diseases, University of Texas M D Anderson Cancer Center, Houston 77030.
出版信息
West J Med. 1994 Oct;161(4):377-82.
Fecal occult blood test kits were distributed throughout the ethnically diverse Hawaiian Islands during a 3-week period in 1989. Occult blood was detected in 1,631 persons (11.8%). At least 83% of the participants with positive tests sought medical advice. Subsequently, 76 (4.7%) were diagnosed as having colorectal adenomas and an additional 1.4% had malignant neoplasms (3 gastric and 20 colorectal adenocarcinomas). Three quarters of the colorectal cancers were localized and node-negative. Participation in this program and the type of diagnostic studies done on participants with positive tests varied according to sex and ethnicity. Therefore, these demographic variables must be considered in designing fecal occult blood screening programs.
1989年，在为期3周的时间里，粪便潜血检测试剂盒被分发到种族多样的夏威夷群岛各地。1631人（11.8%）检测出潜血。检测呈阳性的参与者中至少83%寻求了医疗建议。随后，76人（4.7%）被诊断患有结肠直肠腺瘤，另有1.4%患有恶性肿瘤（3例胃癌和20例结肠直肠癌）。四分之三的结肠直肠癌为局限性且无淋巴结转移。参与该项目以及对检测呈阳性的参与者所做的诊断研究类型因性别和种族而异。因此，在设计粪便潜血筛查项目时必须考虑这些人口统计学变量。
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