无症状患者中通过潜血试验检测出的大肠癌分布情况。

Distribution of large-bowel cancers detected by occult blood test in asymptomatic patients.

作者信息

Nivatvongs S, Gilbertsen V A, Goldberg S M, Williams S E

出版信息

Dis Colon Rectum. 1982 Jul-Aug;25(5):420-1. doi: 10.1007/BF02553645.

Abstract

A randomized, controlled study on occult blood in stool was conducted in 48,000 asymptomatic participants, ages 50 to 80 years. Those with positive hemoccult test results underwent a complete colonic workup including colonoscopy and, in some cases, an air-contrast barium-enema examination when total colonoscopy could not be accomplished. From April 1976 to December 1980, 113 patients (62 men and 51 women), with an average age of 66 years, were found to have invasive carcinomas of the large bowel: right colon--25 per cent, transverse colon (included both flexures)--9 per cent, descending colon--10 percent, sigmoid and rectosigmoid--42 per cent, rectum--12 per cent, anal canal--2 per cent. The stages of the cancers were: Dukes' A--57 per cent, Dukes' B--21 per cent, Dukes' C--19 per cent, Dukes' D--3 per cent. The findings suggest that a complete colonic workup is required for the detection and diagnosis of large-bowel cancers in asymptomatic patients.

摘要

对48000名年龄在50至80岁的无症状参与者进行了一项关于大便潜血的随机对照研究。潜血试验结果呈阳性的患者接受了包括结肠镜检查在内的完整结肠检查，在某些情况下，当无法完成全结肠镜检查时，还进行了气钡双重造影灌肠检查。从1976年4月至1980年12月，发现113例患者（62名男性和51名女性）患有大肠浸润性癌，平均年龄66岁：右半结肠——25%，横结肠（包括两个弯曲部）——9%，降结肠——10%，乙状结肠和直肠乙状结肠部——42%，直肠——12%，肛管——2%。癌症分期为：杜克A期——57%，杜克B期——21%，杜克C期——19%，杜克D期——3%。研究结果表明，对于无症状患者的大肠癌检测和诊断，需要进行完整的结肠检查。