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[儿童先天性球形红细胞增多症]

[Congenital spherocytosis in children].

作者信息

Nowaczyk-Michalak A, Kołtan S, Kołtan A, Wysocki M, Pilecki O

机构信息

Katedry i Kliniki Chorób Dzieci Ak. Med. w Bydgoszczy.

出版信息

Wiad Lek. 1994 May;47(9-10):325-8.

PMID:7817587
Abstract

The clinical course and effects of treatment of congenital spherocytosis (CS) were analyzed in 28 children. In 10 cases the disease ran a severe clinical course. Jaundice, anaemia, and splenomegaly were the most frequent clinical signs which were significantly intensified during haemolytic crises. In 14 cases splenectomy was performed, obtaining in all children a regression of jaundice and anaemia. Before the operation two children were vaccinated with Pneumo 23. In asplenic children Debecillin was prophylactically used. Serious infectious complications were observed only in one patient.

摘要

对28例儿童先天性球形红细胞增多症(CS)的临床病程及治疗效果进行了分析。10例患儿病情严重。黄疸、贫血和脾肿大是最常见的临床症状,在溶血危象期间明显加重。14例行脾切除术,所有患儿的黄疸和贫血均消退。术前2例患儿接种了23价肺炎球菌多糖疫苗。对无脾患儿预防性使用了德贝西林。仅1例患者出现严重感染并发症。

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