Hernán Silva I, Jerez C S, Ruiz T A, Seguel L M, Court L J, Labarca B R
Clínica Pisquiátrica, Universidad de Chile, Santiago.
Actas Luso Esp Neurol Psiquiatr Cienc Afines. 1994 Sep-Oct;22(5):200-2.
Drug-naive schizophrenic patients lacked abnormal involuntary movements. Chronic neuroleptic treatment was associated in 4% of the cases with Tardive Dyskinesia (TD). These findings suggest that schizophrenia, at least in its early stages, is not contributing to the appearance of Tardive Dyskinesia, and also underscore the importance of using the lowest effective neuroleptico dose to reduce the risk of that syndrome.
未服用过药物的精神分裂症患者没有异常的不自主运动。在4%的病例中,慢性抗精神病药物治疗与迟发性运动障碍(TD)有关。这些发现表明,精神分裂症,至少在其早期阶段,不会导致迟发性运动障碍的出现,这也强调了使用最低有效剂量的抗精神病药物以降低该综合征风险的重要性。