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[用贝氏抗原进行淋巴细胞转化试验(贝氏淋巴细胞转化试验)在新旧费辛格-勒鲁瓦-赖特综合征及强直性脊柱炎中的应用。补充研究]

[The lymphocyte transformation test with the bedsonian antigen (bedsonian LTT) in old and recent Fiessinger-Leroy-Reiter syndromes and in ankylsoing spondylarthritis. Additional study].

作者信息

Pattin S, Durosoir J L, Thabaut A, Doury P

出版信息

Rev Rhum Mal Osteoartic. 1976 Jun;43(6):407-10.

PMID:781787
Abstract

The lymphoblastic transformation test in the presence of bedsonian antigen was positive in 72 per cent of the cases confirmed Fiessinger-Leroy-Reiter syndrome, while it was negative in all the controls. This test remains positive over a long period since it was found to be positive in 69.75 per cent of old cases of FLR syndrome diagnosed 13-17 years previously. In cases of post-Reiter ankylosing spondylarthritis (ASp), the bedonian LTT was positive with equal frequency as in cases of FLR syndrome not complicated by ASp (68.4 per cent). On the other hand, in the cases of ASp without known history of FLR the test was positive much less frequently (17.7 per cent). There was no significant difference between the positivity rate of the bedsosian LTT in cases of pure axial ASp and in cases of ASP with peripheral lesions, neither in the group with post-Reiter ASp nor in the group with idiopathic ASp. In addition to its diagnostic value, this test is of great value in the epidemiological study of the group of rheumatic diseases that includes the FLR syndrome and ASp.

摘要

在存在贝宗体抗原的情况下,淋巴细胞转化试验在确诊为菲辛格 - 勒鲁瓦 - 赖特综合征的病例中有72%呈阳性,而在所有对照中均为阴性。该试验在很长一段时间内保持阳性,因为在13至17年前诊断的FLR综合征老病例中,有69.75%被发现呈阳性。在赖特后强直性脊柱炎(ASp)病例中,贝宗体淋巴细胞转化试验阳性频率与未并发ASp的FLR综合征病例相同(68.4%)。另一方面,在无已知FLR病史的ASp病例中,该试验阳性频率要低得多(17.7%)。在单纯轴向ASp病例和伴有周围病变的ASp病例中,贝宗体淋巴细胞转化试验阳性率在赖特后ASp组和特发性ASp组中均无显著差异。除了其诊断价值外,该试验在包括FLR综合征和ASp在内的一组风湿性疾病的流行病学研究中具有重要价值。

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1
[The lymphocyte transformation test with the bedsonian antigen (bedsonian LTT) in old and recent Fiessinger-Leroy-Reiter syndromes and in ankylsoing spondylarthritis. Additional study].[用贝氏抗原进行淋巴细胞转化试验(贝氏淋巴细胞转化试验)在新旧费辛格-勒鲁瓦-赖特综合征及强直性脊柱炎中的应用。补充研究]
Rev Rhum Mal Osteoartic. 1976 Jun;43(6):407-10.
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Infect Immun. 1981 Oct;34(1):98-104. doi: 10.1128/iai.34.1.98-104.1981.
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Clin Rheumatol. 1987 Sep;6(3):384-90. doi: 10.1007/BF02206837.