Sage J I, Mark M H
Department of Neurology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick 08903.
Ann Neurol. 1995 Jan;37(1):120-2. doi: 10.1002/ana.410370124.
We followed 4 patients with Parkinson's disease and severe, intermittent, drenching sweats. One patient was studied with serial plasma levodopa levels and simultaneous clinical examinations. She was observed during a severe sweating episode; this was associated with subtherapeutic plasma levodopa levels (low dopa state). All 4 patients' sweats responded favorably to the institution of agonist therapy. Drenching sweats should be considered part of the spectrum of off-period levodopa-related fluctuations in Parkinson's disease.
我们跟踪了4例患有帕金森病且伴有严重、间歇性大汗淋漓症状的患者。对其中1例患者进行了系列血浆左旋多巴水平测定及同步临床检查。在一次严重出汗发作期间对她进行了观察；这与血浆左旋多巴水平低于治疗量（低多巴状态）有关。所有4例患者的出汗症状在开始使用激动剂治疗后均有良好反应。大汗淋漓应被视为帕金森病中与左旋多巴停药期相关波动症状谱的一部分。
