Palosuo T, Kano K, Anthone S, Gerbasi J R, Milgrom F
Transplantation. 1976 Apr;21(4):312-6. doi: 10.1097/00007890-197604000-00007.
Sera from patients who had received renal allografts were studied for the presence of circulating immune complexes by using platelet aggregation technique combined with density gradient centrifugation. A simple and highly reproducible modification of the platelet aggregation technique, employing the use of relatively small amounts of blood from pretested donors as the source for platelets, is described. Immune complexes were detected in post-transplantation sera from 3 out of 16 patients. The development of a persistent immune complex state as a consequence of grafting was concluded in one patient.
采用血小板聚集技术结合密度梯度离心法，对接受同种异体肾移植患者的血清进行循环免疫复合物检测。本文描述了一种简单且高度可重复的血小板聚集技术改良方法，该方法使用来自预先检测过的供体的相对少量血液作为血小板来源。在16例患者中的3例移植后血清中检测到免疫复合物。得出结论，一名患者因移植出现了持续性免疫复合物状态。
