远霉素和苯并内酰胺可抑制1型人类免疫缺陷病毒（HIV-1）的细胞杀伤作用。
Teleocidins and benzolactams inhibit cell killing by human immunodeficiency virus type 1 (HIV-1).
作者信息
Endo Y, Ohno M, Hirano M, Fujiwara T, Sato A, Hinuma Y, Shudo K
机构信息
Faculty of Pharmaceutical Sciences, University of Tokyo, Japan.
出版信息
Biol Pharm Bull. 1994 Aug;17(8):1147-9. doi: 10.1248/bpb.17.1147.
PMID:7820129
Abstract
Teleocidin B-4 and structurally related synthetic benzolactams were found to be potent inhibitors of cell killing by HIV-1. One of the benzolactams, (-)-BL-V8-310, showed a high selectivity index.
摘要
发现远距霉素B-4和结构相关的合成苯并内酰胺是HIV-1细胞杀伤的有效抑制剂。其中一种苯并内酰胺，(-)-BL-V8-310，显示出高选择性指数。
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