Donohue J P, Thornhill J A, Foster R S, Bihrle R
Indiana University Medical Center, Department of Urology, Indianapolis 46202-5250.
World J Urol. 1994;12(4):187-9. doi: 10.1007/BF00185669.
A total of 710 patients underwent postchemotherapy retroperitoneal lymph-node dissection (RPLND) from 1965 to 1992. Ten patients, all with bulky disease, required aortic replacement either postoperatively (n = 3) or during RPLND (n = 7). The principal risk factor for aortic rupture after RPLND was an extended subadventitial aortic dissection made necessary by tumor fixation. Also, duodenal enterotomy or extensive violation of the bowel serosa was a further risk for aortoenteric fistula. Prospective aortic grafting may be indicated in the presence of these risk factors. In our four elective cases, there was no further vascular or bowel complication. Omental interposition further protects against fistula formation. Although rarely indicated except under the most extenuating circumstances, the exposure requirements of RPLND permit aortic grafting as a relatively straightforward procedure that is feasible and well tolerated in this small subset of patients.
1965年至1992年期间,共有710例患者接受了化疗后腹膜后淋巴结清扫术(RPLND)。10例患者均患有大块肿瘤,术后(n = 3)或在RPLND期间(n = 7)需要进行主动脉置换。RPLND后主动脉破裂的主要危险因素是肿瘤固定导致的外膜下主动脉夹层扩展。此外,十二指肠切开术或肠浆膜的广泛侵犯是主动脉肠瘘的另一危险因素。存在这些危险因素时,可能需要进行前瞻性主动脉移植。在我们的4例择期病例中,没有进一步的血管或肠道并发症。网膜植入可进一步预防瘘管形成。尽管除了在最特殊的情况下很少有必要,但RPLND的暴露要求使主动脉移植成为一种相对简单的手术,在这一小部分患者中是可行的且耐受性良好。