Jenkins J, Wheeler V, Albright L
Cancer and Human Genome Nursing Services, NIH, Bethesda, MD 20892.
Cancer Nurs. 1994 Dec;17(6):447-56.
Advances in molecular biology and technology now being made will open the way to using gene transfer as a therapeutic option for patients with cancer. Since there are > 5,000 known genetic diseases, the potential impact of these techniques is enormous. Possibilities for the application of gene therapy are emerging and along with them complex safety, ethical, and financial issues that will require resolution. Many of these concerns will become relevant to the oncology nurse, who will need to understand the science, ethics, safety considerations, and impact of this experimental therapy on the patient. Since gene therapy is a rapidly evolving method of treatment, it will be a challenge to remain up to date and knowledgeable.
目前正在取得的分子生物学和技术进展将为把基因转移用作癌症患者的一种治疗选择开辟道路。由于已知有5000多种遗传疾病,这些技术的潜在影响是巨大的。基因治疗的应用可能性正在出现,与之相伴的还有复杂的安全、伦理和财务问题,这些问题需要得到解决。其中许多问题将与肿瘤学护士相关,他们需要了解这种实验性治疗的科学、伦理、安全考量以及对患者的影响。由于基因治疗是一种迅速发展的治疗方法,要跟上最新进展并掌握相关知识将是一项挑战。