Rico H, Relea P, Crespo R, Revilla M, Villa L F, Arribas I, Usabiaga J
Department of Medicine, School of Medicine, Universidad de Alcalá de Henares, Madrid, Spain.
J Bone Joint Surg Br. 1995 Jan;77(1):148-51.
We studied nutritional deficits, using as markers the levels of transferrin, retinol-binding protein, and prealbumin, in 20 women with osteoporotic hip fractures (type II), 40 women with vertebral fractures (type I), and two groups of age-matched control subjects. The concentrations of all three nutritional markers were lower in the two groups of patients than in their matched controls, and in type-I as compared with type-II osteoporosis. In the osteoporotic patients, simple linear regression showed a significant correlation between the variables which we studied (r2 ranged from 0.5 to 0.7; p < 0.001), the best correlation being between prealbumin and retinol-binding protein in type-II osteoporosis. Our results suggest that there is a more marked nutritional deficit in type-II than in type-I osteoporosis.
我们以转铁蛋白、视黄醇结合蛋白和前白蛋白水平作为指标，研究了20例骨质疏松性髋部骨折（II型）女性、40例椎体骨折（I型）女性以及两组年龄匹配的对照受试者的营养缺乏情况。两组患者的所有三种营养指标浓度均低于其匹配的对照组，且I型骨质疏松患者低于II型。在骨质疏松患者中，简单线性回归显示我们所研究的变量之间存在显著相关性（r2范围为0.5至0.7；p < 0.001），II型骨质疏松中前白蛋白与视黄醇结合蛋白之间的相关性最佳。我们的结果表明，II型骨质疏松比I型骨质疏松存在更明显的营养缺乏。
