骨质疏松症中的营养生化标志物。
Biochemical markers of nutrition in osteoporosis.
作者信息
Rico H, Relea P, Revilla M, Hernandez E R, Arribas I, Villa L F
机构信息
Department of Medicine, Principe de Asturias University Hospital, Alcaldá de Henares University, Madrid, Spain.
出版信息
Calcif Tissue Int. 1993 Apr;52(4):331-3. doi: 10.1007/BF00296660.
Thirty-six women with vertebral osteoporosis showed significantly decreased levels of biochemical markers of nutrition, transferrin (P < 0.001), prealbumin (P < 0.001), retinol binding-protein (P < 0.001), and fibronectin (P < 0.001), compared with 40 healthy women of similar age. Multiple regression analysis showed a significant (R2 = 0.509; P = 0.0068) correlation between bone mineral content and biochemical markers of nutrition in the osteoporotic patients but not in the control group. These data suggest that postmenopausal osteoporosis may be associated with a nutritional deficiency.
与40名年龄相仿的健康女性相比，36名患有脊椎骨质疏松症的女性体内营养生化指标水平显著降低，包括转铁蛋白（P < 0.001）、前白蛋白（P < 0.001）、视黄醇结合蛋白（P < 0.001）和纤连蛋白（P < 0.001）。多元回归分析显示，骨质疏松症患者的骨矿物质含量与营养生化指标之间存在显著相关性（R2 = 0.509；P = 0.0068），而对照组则无此相关性。这些数据表明，绝经后骨质疏松症可能与营养缺乏有关。
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