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慢性疲劳综合征、多发性硬化症和抑郁症中的神经心理学损伤

Neuropsychological impairments in chronic fatigue syndrome, multiple sclerosis, and depression.

作者信息

DeLuca J, Johnson S K, Beldowicz D, Natelson B H

机构信息

Department of Research and Psychology, Kessler Institute for Rehabilitation, West Orange, New Jersey.

出版信息

J Neurol Neurosurg Psychiatry. 1995 Jan;58(1):38-43. doi: 10.1136/jnnp.58.1.38.

Abstract

To examine the degree and nature of cognitive impairments in chronic fatigue syndrome, a comprehensive neuropsychological battery was given to patients with chronic fatigue syndrome, multiple sclerosis, depressed patients, and healthy controls. The battery included tests of attention and concentration, information processing speed, verbal and visual memory, intellectual ability, and concept formation. Measures of depression and anxiety were also obtained. The chronic fatigue syndrome group did not differ from the depressed group in overall neuropsychological performance, but differed from the multiple sclerosis and control groups. The most significant impairment was in information processing speed in the chronic fatigue syndrome group. Depression and anxiety were not related to neuropsychological performance. The influence of reduced information processing on other areas of cognition is discussed.

摘要

为了研究慢性疲劳综合征中认知障碍的程度和性质,对慢性疲劳综合征患者、多发性硬化症患者、抑郁症患者和健康对照组进行了全面的神经心理测试。测试包括注意力和专注力、信息处理速度、言语和视觉记忆、智力能力以及概念形成等方面的测试。还获取了抑郁和焦虑的测量数据。慢性疲劳综合征组在整体神经心理表现上与抑郁症组没有差异,但与多发性硬化症组和对照组不同。慢性疲劳综合征组最显著的损伤在于信息处理速度。抑郁和焦虑与神经心理表现无关。文中讨论了信息处理能力下降对其他认知领域的影响。

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本文引用的文献

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An inventory for measuring depression.一份用于测量抑郁的量表。
Arch Gen Psychiatry. 1961 Jun;4:561-71. doi: 10.1001/archpsyc.1961.01710120031004.
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