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新生儿破伤风:持续存在的挑战。

Neonatal tetanus: a continuing challenge.

机构信息

Department of Pediatrics, M. L. N. Medical College, Allahabad, U.P., India.

出版信息

Indian J Pediatr. 2012 Dec;79(12):1648-50. doi: 10.1007/s12098-011-0666-8. Epub 2012 Jan 7.

Abstract

The authors retrospectively analyzed the case records of all the newborns admitted with the diagnosis of neonatal tetanus (NT) over a period of 36 mo. A total of 27 cases of neonatal tetanus were admitted over a period of 36 mo. Out of these 27 neonates, 17 died and thus the overall mortality was 63%. The mean age of onset of symptoms in those who survived was 8.1 ± 2.02 d whereas in those who died was 5.7 ± 1.39 d, which was statistically significant (p = 0.001). The babies with age of onset <7 d were almost 5 times more likely to die than those manifesting at 7 d or later. Thus, NT is still contributing to neonatal deaths especially in the backward areas of the country and onset of symptoms within a wk of birth is a very high risk factor for mortality.

摘要

作者回顾性分析了在 36 个月期间因新生儿破伤风(NT)入院的所有新生儿的病例记录。在 36 个月期间共收治了 27 例新生儿破伤风。其中 17 例死亡,总死亡率为 63%。存活者的症状发作平均年龄为 8.1±2.02d,而死亡者的症状发作平均年龄为 5.7±1.39d,差异具有统计学意义(p=0.001)。发病年龄<7d 的婴儿死亡的可能性几乎是发病年龄为 7d 或更晚的婴儿的 5 倍。因此,NT 仍然导致新生儿死亡,尤其是在该国的落后地区,出生后 1 周内出现症状是一个非常高的死亡风险因素。

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