Elmore S K, Burr R
J Nurs Meas. 1993 Spring;1(1):81-100.
The role circadian rhythms play in mental health, sleep, human development and aging, pharmacologic efficacy, immune function, and cardiovascular health makes them a natural focus of nursing research. Integration of chronobiologic concepts into nursing care demands sound empirical support. Nevertheless, issues such as detection of linear trends, the fit of circadian data to a cosinor model and circular distributions, add complexity to the collection, analysis and interpretation of circadian rhythm data. The purpose of this paper is to convey an informed understanding of ways in which to deal with this intricate assembly of issues.
昼夜节律在心理健康、睡眠、人类发育与衰老、药物疗效、免疫功能及心血管健康方面所起的作用，使其成为护理研究的一个自然焦点。将生物钟学概念融入护理工作需要可靠的实证支持。然而，诸如线性趋势的检测、昼夜节律数据与余弦曲线模型及圆形分布的拟合等问题，增加了昼夜节律数据收集、分析及解读的复杂性。本文旨在让读者对处理这一复杂问题组合的方法有深入了解。
