Ratnatnga N, Ramadasa S
Department of Pathology, Faculty of Medicine, University of Peradeniya, Sri Lanka.
Ceylon Med J. 1993 Sep;38(3):113-6.
Paraffin sections of 14 specimens of poorly differentiated tumours of the thyroid were stained for thyroglobulin using polyclonal antibodies and a streptavidin-biotin peroxidase staining system. The better differentiated areas showed positive staining, while the poorly differentiated areas gave weakly positive or negative staining. Thyroglobulin staining is useful in attributing a thyroid epithelial cell origin to a tumour, but negative staining does not exclude this.
