Sturm U, Grossmann H, Schuh D, Zotter S, Müller M
Institut für Pathologische Anatomie, Medizinischen Akademie Dresden.
Zentralbl Allg Pathol. 1989;135(3):281-5.
An antiserum against human thyroglobulin isolated by gelfiltration from the human thyroid gland was raised in rabbits. The specificity of the antiserum to detect human thyroglobulin was determined by an immunoperoxidase technique on formalin-fixed and paraffin-embedded tissue sections of 17 primary thyroid carcinomas and 80 carcinomas of other origins, such as pancreas, colon, breast, bladder, ovary, testis, and larynx. Positive reactions to immunological staining were recorded only from differentiated thyroid carcinomas, while no reactions were exhibited by the other malignant tumours tested in this study.
通过凝胶过滤从人甲状腺中分离出的人甲状腺球蛋白抗血清在兔体内产生。采用免疫过氧化物酶技术，对17例原发性甲状腺癌以及80例其他来源（如胰腺、结肠、乳腺、膀胱、卵巢、睾丸和喉）的癌组织的福尔马林固定石蜡包埋组织切片进行检测，以确定该抗血清检测人甲状腺球蛋白的特异性。仅在分化型甲状腺癌中记录到免疫染色的阳性反应，而本研究中检测的其他恶性肿瘤均未出现反应。
