Cavalli G, De Gregorio C, Magazù A, Nicosia S, Carerj S, Arrigo F, Oreto G
Istituto Pluridisciplinare di Clinica Medica, Cattedra di Cardiologia, Università di Messina.
G Ital Cardiol. 1994 Nov;24(11):1371-8.
The evaluation of mitral valve area (MVA) in patients with mitral stenosis represents the main purpose of any diagnostic method, provided that MVA is a key parameter to indicate the need for valve surgery. The aim of this study was to assess whether the presence of aortic regurgitation associated with mitral stenosis affects the MVA measurement by left atrial pressure half time (PHT).
Eighty-nine patients with mitral valve stenosis (68 females and 21 males, mean age 53.6 +/- 12.1 years), were studied. Fourty-eight patients (36 females and 12 males) had a concomitant aortic regurgitation (AR group), whereas 41 patients (32 females and 9 males) did not reflect any aortic valve involvement (no-AR group). Aortic regurgitation was graded on the basis of color flow analysis. The majority of patients had a slight to moderate regurgitation. MVA determination was carried out using both Hatle formula (220/PHT) and planimetric measurement in parasternal short axis view.
Statistical analysis demonstrated a good correlation between the 2 MVA measurement in both groups (IA group: r = 0.9, p < 0.0001, SSE = 0.21 cm2, y = 0.91x + 0.05; no-IA group r = 0.92, p < 0.0001, SSE = 0.22 cm2, y = 0.92x + 0.04). The concomitant aortic valve disease did not affect in any way the MVA measurement by means of the PHT method.
The Doppler derived method appears to be reliable for estimating the mitral valve area in patients with mitral stenosis even in the presence of aortic regurgitation.
二尖瓣狭窄患者二尖瓣瓣口面积(MVA)的评估是任何诊断方法的主要目的,因为MVA是表明是否需要进行瓣膜手术的关键参数。本研究的目的是评估与二尖瓣狭窄相关的主动脉瓣反流的存在是否会影响通过左心房压力减半时间(PHT)测量MVA。
对89例二尖瓣狭窄患者(68例女性,21例男性,平均年龄53.6±12.1岁)进行研究。48例患者(36例女性,12例男性)伴有主动脉瓣反流(AR组),而41例患者(32例女性,9例男性)未显示任何主动脉瓣受累(无AR组)。根据彩色血流分析对主动脉瓣反流进行分级。大多数患者有轻度至中度反流。使用哈特公式(220/PHT)和胸骨旁短轴视图中的平面测量法测定MVA。
统计分析表明两组中两种MVA测量方法之间具有良好的相关性(AR组:r = 0.9,p < 0.0001,SSE = 0.21 cm²,y = 0.91x + 0.05;无AR组:r = 0.92,p < 0.0001,SSE = 0.22 cm²,y = 0.92x + 0.04)。伴发的主动脉瓣疾病对通过PHT法测量MVA没有任何影响。
即使存在主动脉瓣反流,多普勒衍生方法似乎对于估计二尖瓣狭窄患者的二尖瓣瓣口面积也是可靠的。