Chuttani C S
Dev Biol Stand. 1976;33:98-101.
Three vaccination trials against typhoid fever were carried out in 1968/69, 1970/71 and 1974 in New Dehli. The vaccine was generally administered in tablet form on three consecutive days. Each new trial consisted of a larger number of killed bacteria: 100.10(9), then 300.10(9) and finally 400.10(9) killed S. typhi. The placebo and vaccinated groups were composed of 6,000 to 7,000 persons, sometimes only children from 6 to 17 years. The number of typhoid fever cases which appeared under normal conditions of infection did not show significant difference between the vaccinated and non-vaccinated subjects during the 18 month period of observation.
1968/69年、1970/71年和1974年在新德里进行了三项伤寒疫苗接种试验。疫苗通常以片剂形式连续三天服用。每项新试验所使用的死菌数量都更多：先是100×10⁹，然后是300×10⁹，最后是400×10⁹个伤寒杆菌死菌。安慰剂组和接种疫苗组由6000至7000人组成，有时仅为6至17岁的儿童。在18个月的观察期内，在正常感染条件下出现的伤寒病例数量在接种疫苗和未接种疫苗的受试者之间没有显著差异。
