口服伤寒灭活疫苗在现场试验中的无效性
Ineffectiveness of an oral killed typhoid vaccine in a field trial.
作者信息
Chuttani C S, Prakash K, Vergese A, Gupta P, Chawla R K, Grover V, Agarwal D S
出版信息
Bull World Health Organ. 1973 Jun;48(6):754-5.
Abstract
A field trial was carried out with a vaccine containing 300x10(9) killed S. typhi (strain Ty58) per tablet. A total of 12 564 children aged 1-15 years were given 3 tablets of the vaccine or a placebo at the rate of one tablet on each of 3 consecutive days. The results indicated that the vaccine, in its present form and at this dosage, gives no protection.
摘要
对一种每片含300×10⁹ 伤寒杆菌（Ty58株）死菌的疫苗进行了现场试验。总共12564名1至15岁的儿童，连续3天每天服用1片，共服用3片该疫苗或安慰剂。结果表明，以目前的形式和剂量，该疫苗没有防护作用。
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本文引用的文献
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Effectiveness of oral killed typhoid vaccine.口服伤寒灭活疫苗的有效性。
Bull World Health Organ. 1971;45(4):445-50.
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