近期发病的1型糖尿病患者对38kD胰岛素分泌颗粒蛋白的T细胞反应性。 - Suppr

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超能文献

T-cell reactivity to 38 kD insulin-secretory granule protein in patients with recent onset type 1 diabetes.

作者信息

Bonifacio E, Boitard C

机构信息

Dept. of Medicine, San Raffaele Hospital Scientific Institute, University of Milano, Italy.

出版信息

J Endocrinol Invest. 1994 Jul-Aug;17(7):559-63. doi: 10.1007/BF03347750.

DOI:10.1007/BF03347750

PMID:7829830

Abstract

摘要

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T-cell reactivity to 38 kD insulin-secretory granule protein in patients with recent onset type 1 diabetes.近期发病的1型糖尿病患者对38kD胰岛素分泌颗粒蛋白的T细胞反应性。

J Endocrinol Invest. 1994 Jul-Aug;17(7):559-63. doi: 10.1007/BF03347750.

T-cell clones from a type-1 diabetes patient respond to insulin secretory granule proteins.一名1型糖尿病患者的T细胞克隆对胰岛素分泌颗粒蛋白有反应。

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T-cell reactivity to 38 kD insulin-secretory-granule protein in patients with recent-onset type 1 diabetes.

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Islet-reactive T cells are a marker of preclinical insulin-dependent diabetes.胰岛反应性T细胞是临床前胰岛素依赖型糖尿病的一个标志物。

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本文引用的文献

Effects of intrathymic injection of organ-specific autoantigens, parietal cells, at the neonatal stage on autoreactive effector and suppressor T cell precursors.新生期胸腺内注射器官特异性自身抗原壁细胞对自身反应性效应和抑制性T细胞前体的影响。

Eur J Immunol. 1993 Apr;23(4):809-14. doi: 10.1002/eji.1830230406.

Glutamic acid decarboxylase 67-reactive T cells: a marker of insulin-dependent diabetes.谷氨酸脱羧酶67反应性T细胞：胰岛素依赖型糖尿病的一个标志物。

J Exp Med. 1993 Feb 1;177(2):535-40. doi: 10.1084/jem.177.2.535.

An autoimmune disease with multiple molecular targets abrogated by the transgenic expression of a single autoantigen in the thymus.一种自身免疫性疾病，其多个分子靶点因胸腺中单一自身抗原的转基因表达而被消除。

J Exp Med. 1993 Aug 1;178(2):419-26. doi: 10.1084/jem.178.2.419.

Detection of pancreatic islet 64,000 M(r) autoantigens in insulin-dependent diabetes distinct from glutamate decarboxylase.在胰岛素依赖型糖尿病中检测到与谷氨酸脱羧酶不同的胰岛64,000 M(r)自身抗原。

J Clin Invest. 1993 Jul;92(1):240-8. doi: 10.1172/JCI116556.

Isolation of nonobese diabetic mouse T-cells that recognize novel autoantigens involved in the early events of diabetes.分离识别参与糖尿病早期事件的新型自身抗原的非肥胖糖尿病小鼠T细胞。

Diabetes. 1994 Jan;43(1):33-9. doi: 10.2337/diab.43.1.33.

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.对谷氨酸脱羧酶的免疫反应与非肥胖糖尿病小鼠的胰岛炎相关。

Nature. 1993 Nov 4;366(6450):72-5. doi: 10.1038/366072a0.

Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins.新诊断糖尿病儿童中的自身抗体可使人类胰岛细胞蛋白发生免疫沉淀。

Nature. 1982 Jul 8;298(5870):167-9. doi: 10.1038/298167a0.

Insulin antibodies in insulin-dependent diabetics before insulin treatment.胰岛素依赖型糖尿病患者在胰岛素治疗前的胰岛素抗体。

Science. 1983 Dec 23;222(4630):1337-9. doi: 10.1126/science.6362005.

In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis.糖尿病性胰岛炎中胰腺自身免疫现象的原位特征及HLA分子的表达

N Engl J Med. 1985 Aug 8;313(6):353-60. doi: 10.1056/NEJM198508083130604.

Lawrence lecture. Death of a beta cell: homicide or suicide?

Diabet Med. 1986 Mar;3(2):119-30. doi: 10.1111/j.1464-5491.1986.tb00722.x.

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