Schill W, Petzoldt D, Kammerl M
Hautarzt. 1976 Aug;27(8):382-90.
Determination of autologous sperm antibodies in the serum of 278 male adults of an unselected andrological patient material is reported. Positive test results were found in 3 patients using the macroscopic agglutination test according to Kibrick (1.1%), in 21 patients using the microscopical agglutination test according to Franklin-Dukes (7.6%), in 2 patients using the immobilization test according to Isojima (0.7%) and in 1 patient using the indirect immunofluorescence technique according to Coons and Kaplan (0.4%). Comparing the macroscopic and microscopic agglutination test a high degree of unspecific agglutinations were found in the latter excluding the microscopical agglutination test for the determination of antibodies. The relatively rare occurrence of autologous sperm antibodies in an unselected andrological patient material points to the fact that immunological methods seem to play no significant role in the diagnosis of male subfertility.