Dvorak H F
J Allergy Clin Immunol. 1976 Jul;58(1 PT. 2):229-40. doi: 10.1016/0091-6749(76)90159-7.
Cutaneous basophil hypersensitivity (CBH) is a distinct form of lymphocyte-mediated hypersensitivity in guinea pigs, separate both from classic delayed hypersensitivity (DH) and from the well-known antibody-mediated reactions. CBH, not DH, is the usual cellular immune response of this species to a wide variety of immunogens (e.g., allografts, certain parasites, and viruses) when these are presented in native form without supplementation with mycobacteria-containing adjuvants, thus attesting to the importance of this response in the guinea pig's overall immune defense mechanism. Basophil-containing, cell-mediated, delayed-onset reactions occur in other species, including man, as well.
皮肤嗜碱性粒细胞超敏反应（CBH）是豚鼠中一种独特的淋巴细胞介导的超敏反应形式，既不同于经典的迟发型超敏反应（DH），也不同于众所周知的抗体介导反应。当各种免疫原（如同种异体移植物、某些寄生虫和病毒）以天然形式呈现而不添加含分枝杆菌的佐剂时，豚鼠对这些免疫原的通常细胞免疫反应是CBH而非DH，这证明了这种反应在豚鼠整体免疫防御机制中的重要性。含嗜碱性粒细胞的细胞介导迟发型反应在包括人类在内的其他物种中也会发生。
