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两岁以下儿童持续性动脉导管的伞形封堵术

Umbrella occlusion of persistent arterial duct in children under two years.

作者信息

Gatzoulis M A, Rigby M L, Redington A N

机构信息

Department of Paediatric Cardiology, Royal Brompton Hospital, London.

出版信息

Br Heart J. 1994 Oct;72(4):364-7. doi: 10.1136/hrt.72.4.364.

Abstract

OBJECTIVE

To assess the use of trans-catheter occlusion of a persistent arterial duct in symptomatic children < 2 years of age.

DESIGN

Descriptive study of selected, non-randomised infants with persistent arterial duct who underwent attempted umbrella occlusion.

SETTING

Tertiary referral centre.

PATIENTS

Between June 1990 and April 1993, 29 young children with a symptomatic persistent arterial duct underwent attempted transcatheter occlusion. Their age ranged from 1.5 to 23 months, with the youngest infant weighing 2.9 kg. The diagnosis was established before operation in all patients by cross sectional echocardiography.

INTERVENTION

Transcatheter occlusion of a haemodynamically important persistent arterial duct was performed with the Rashkind ductal umbrella. In the past year the front loading technique has been used to place the 12 mm umbrella through a 6 F (French) sheath and the 17 mm device through a 8 F sheath so extending the indications for their use.

RESULTS

Umbrellas were successfully placed in 25 (86.2%) infants and there was symptomatic improvement in all. There were no deaths or severe complications. The four failures occurred early in the series. They were caused by kinking of the 11 F sheath in two cases and embolisation into the left pulmonary artery in one case. The procedure was abandoned in the fourth case because of a large duct. Only three of the 25 patients had small residual shunts at one year follow up (all with 17 mm devices) but no stenosis or turbulence was noted in any of the patients.

CONCLUSION

The transcatheter occlusion of persistent arterial duct in young children with symptoms is a safe alternative to surgery. The new front loading umbrella technique enables successful ductal closure in even smaller infants than earlier devices.

摘要

目的

评估对2岁以下有症状儿童采用经导管封堵动脉导管未闭的效果。

设计

对经选择的、未随机分组的动脉导管未闭婴儿进行伞封堵术的描述性研究。

地点

三级转诊中心。

患者

1990年6月至1993年4月期间,29例有症状的动脉导管未闭幼儿接受了经导管封堵术尝试。他们的年龄在1.5至23个月之间,最小的婴儿体重为2.9千克。所有患者术前均通过超声心动图确诊。

干预

采用Rashkind动脉导管伞对具有血流动力学意义的动脉导管未闭进行经导管封堵。在过去一年中,采用前端加载技术通过6F(法国)鞘管置入12mm的伞,通过8F鞘管置入17mm的装置,从而扩大了其使用指征。

结果

25例(86.2%)婴儿成功置入伞,所有患儿症状均有改善。无死亡或严重并发症发生。4例失败发生在该系列研究早期。2例是由于11F鞘管扭结,1例是栓子栓塞入左肺动脉。第4例因导管粗大而放弃手术。25例患者中只有3例在1年随访时有小的残余分流(均使用17mm装置),但所有患者均未发现狭窄或血流紊乱。

结论

对有症状的幼儿经导管封堵动脉导管未闭是一种安全的手术替代方法。新的前端加载伞技术能够在比早期装置更小的婴儿中成功实现导管闭合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b27/1025548/34bec85b4669/brheartj00007-0057-a.jpg

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