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Do anticonvulsants alter the natural course of epilepsy? Treatment should be started as early as possible.

作者信息

Reynolds E H

机构信息

Centre for Epilepsy, Maudsley Hospital, London.

出版信息

BMJ. 1995 Jan 21;310(6973):176-7. doi: 10.1136/bmj.310.6973.176.

DOI:10.1136/bmj.310.6973.176
PMID:7833760
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2548563/
Abstract
摘要

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How do we manage the first seizure in adults?我们如何处理成人的首次癫痫发作?
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本文引用的文献

1
Randomized clinical trial on the efficacy of antiepileptic drugs in reducing the risk of relapse after a first unprovoked tonic-clonic seizure. First Seizure Trial Group (FIR.S.T. Group).
Neurology. 1993 Mar;43(3 Pt 1):478-83. doi: 10.1212/wnl.43.3_part_1.478.
2
Early treatment and prognosis of epilepsy.癫痫的早期治疗与预后
Epilepsia. 1987 Mar-Apr;28(2):97-106. doi: 10.1111/j.1528-1157.1987.tb03633.x.
3
The course of untreated epilepsy.未经治疗的癫痫病程。
BMJ. 1988 Oct 15;297(6654):948-50. doi: 10.1136/bmj.297.6654.948.
4
Comprehensive primary health care antiepileptic drug treatment programme in rural and semi-urban Kenya. ICBERG (International Community-based Epilepsy Research Group).肯尼亚农村和半城市地区的综合初级卫生保健抗癫痫药物治疗项目。国际社区癫痫研究小组(ICBERG)
Lancet. 1991 Feb 16;337(8738):406-9. doi: 10.1016/0140-6736(91)91176-u.
5
Alteration of long-lasting structural and functional effects of kainic acid in the hippocampus by brief treatment with phenobarbital.苯巴比妥短期治疗对海马中红藻氨酸持久结构和功能效应的改变。
J Neurosci. 1992 Nov;12(11):4173-87. doi: 10.1523/JNEUROSCI.12-11-04173.1992.
6
First seizure in adults: to treat or not to treat.成人首次癫痫发作:治疗与否
Clin Neurol Neurosurg. 1992;94 Suppl:S61-3. doi: 10.1016/0303-8467(92)90024-w.