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一名接受电休克治疗、服用氯氮平和咖啡因的患者出现室上性心动过速。

Supraventricular tachycardia in a patient receiving ECT, clozapine, and caffeine.

作者信息

Beale M D, Pritchett J T, Kellner C H

机构信息

Medical University of South Carolina, Department of Psychiatry and Behavioral Sciences, Charleston 29425.

出版信息

Convuls Ther. 1994 Sep;10(3):228-31.

PMID:7834261
Abstract

A patient receiving electroconvulsive therapy (ECT), clozapine, and intravenous caffeine sodium benzoate developed supraventricular tachycardia. This was rapidly treated with intravenous verapamil. Subsequent maintenance ECT given without caffeine was well tolerated. We believe the combination of clozapine and caffeine at the time of ECT was responsible for the arrhythmia.

摘要

一名接受电休克治疗(ECT)、氯氮平及静脉注射苯甲酸钠咖啡因的患者发生了室上性心动过速。静脉注射维拉帕米迅速控制了病情。随后在无咖啡因情况下进行的维持性ECT治疗耐受性良好。我们认为ECT时氯氮平与咖啡因联用是导致心律失常的原因。

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Neuropsychopharmacol Rep. 2019 Mar;39(1):36-40. doi: 10.1002/npr2.12039. Epub 2018 Nov 16.
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Clozapine induced supra ventricular tachycardia.氯氮平诱发室上性心动过速。
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Electroconvulsive therapy for the treatment of clozapine nonresponders suffering from schizophrenia--an open label study.
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